Natural or Synthetic Hormones?
Hormones are biomolecules that are involved in a variety of activities of living organisms as well as in their development. They are secreted by tissues in our body through the endocrine glands and they are transported through the blood, to the points where they act. Hormones have different effects on the body. For example, they help with body development, metabolism, sexual function, reproduction, etc. Their role in the signal transfer process from one cell to another is also important. This is achieved by binding hormones on special receptors. Overproduction or decreased production of the corresponding hormone causes a hormonal disorder in the body, which usually results in the manifestation of clinical symptoms.
A large number of women have received or are receiving treatments with synthetic hormones, namely Synthetic Hormone Replacement Therapy. Synthetic Progesterone, for example, is actually Progestins, Progestogens, Progesteroids, Medroxyprogesterone and many more, and synthetic estrogens, estrogen metabolites of horses, estrogens from the urine of pregnant mares, which have nothing to do with Human Estrogens.
The manufacturers themselves describe the side effects on the form in their formulations and ongoing studies report the toxicity of these preparations even in the development of Endometrial, Breast and Ovarian cancer. Finally, Synthetic Hormone Replacement Therapies not only increase the risk of developing Cancer, but they are also responsible for Cardiovascular Disease (the leading cause of death worldwide) and Stroke.
But the hormones that are produced in our body do just the opposite. They protect us. Natural or Biomimetic or Bioidentical Hormones are made in the laboratory but have the same molecular structure as the hormones which are made and used by our body, unlike synthetic hormones which are intentionally different.
Their production starts from plant raw materials such as fruits of nature, namely yam and soy. The natural bioidentical estrogens, progesterone, testosterone, DHEA, pregnenolone are provided in specialized pharmacies and are administered by specialized centers and doctors.
What are the advantages of natural biomimetic hormones over synthetic hormones?
The great impact of natural or bioidentical hormones is due to the fact that they are natural and so our body can metabolize them, as it does with its own, without side effects.
Natural hormones (biomimetics) bind to our hormone receptors, just like the key to a lock, thus giving an immediate effect, in contrast to conventional Hormone Rehabilitation therapy, where synthetic hormones bind to hormone receptors and not only, but also to other steroid receptor sites, with a final result, not just the indirect result, but also a multitude of side effects.
Another great advantage of natural hormones (biomimetics) is that they can be measured and so we have more accurate levels of hormones in the blood and even more accurate is the measurement, when it is done in saliva.
Finally, there is no more dramatic proof of the safety of natural hormones (biomimetics) than pregnancy. The hormonal process in pregnancy is extreme. Estrogen levels increase tenfold, progesterone by 100, growth hormone and testosterone by 20%. And of course estriol, the hormone that increases in pregnancy and which we administer in the preparations of natural – biomimetic estrogens, has been proven to be extremely safe for breast cancer.
- Adams, Μ. R., et al. «Medroxyprogesterone acetate antagonizes inhibitory effects of conjugatedequine estrogens οτι coronary artery atherosclerosis.» Arterioscler Thromb Vαsc ΒίοΙ, January 1997, 17 (1): 217-21.
- Antonijevic, Irina, et al. «Modulation of the sleep electroencephalogram by estrogen replacement ίτι postmenopausal women.» Americαn Journαl ΟΙ Obstetrics αnd Gynecology, February 2000: 277.
- Aparasu, R. R. «Visits to office-based physicians ίη the United States for medication-related morbidity.» Journαl ΟΙ the Americαn Phαrm Asso, May- June 1999,39 (3): 332-7.
- Araneo, Β., et al. «DHEAS as an effectiνe νaccine adjuνant ίη elderly humans.» Annαls ΟΙ the New York Acαdemy ΟΙ Sciences, 1995, 774: 232-48.
- Arlt, W, et al. «Dehydroepiandrosterone replacement ίτι women wίth adrenal insufficiency.» New Englαnd Joumαl ΟΙ Medicine, September 30, 1999,341 (14): 1013-20.
- Badwe, R. Α., et al. «Timing of surgery during menstrual cycle and surviνal of premenopausal women wίth operable breast cancer.» Lαncet, 1991, 337: 1261-4.
- Bailar, ]ohn C., and Gornik, Heather. «Cancer undefeated.» New Englαnd Journαl oJMedicine, May 29,1997,336 (22): 1569-74.
- Barrett-Connor, Ε., et al. «The epidemiology ofDHEAS and cardioνascular disease.» Annαls oJ the Νενν York Acαdemy oJ Sciences, 1995, 774: 259-70.
- Bartsch, C., and Bartsch, Η. «Melatonin ίn cancer patients and ίn tumor- bearing animals.» Advances ίπ Exper Med ΒίοΙ, 1999,467: 247-64.
- Batt, Sharon, and Gross, Liza. «Cancer, Inc.» Sierrα Mαgαzine, September/Oc- tober 1999: 36.
- Baulieu, Ε. Ε., et al. «Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: Contribution of the DHEAge Study to a sociobiomedical issue.» Proceedings oJ the Nαtional Acαdemy oJ Sciences USA, Αρτί] 11,2000,97 (8): 4279-84.
- Baum, Α. L. «Selectiνe serotonin-reuptake inhibitors ίn pregnancy and lactation.» Hαrναrd Review oJ Psychiαtry, September 1996,4 (3): 117-25.
- Bilimoria, Μ. Μ., et al. »Estrogen replacement therapy and breast cancer: analysis of age of onset and tumor characteristics.» Annαls oJ Surgicαl On cology, 1999,6: 200-7
- Bluming, Α. Ζ., et al. »Hormone replacement therapy ίn women with preνiously treated Ρήmary breast cancer.» Proceedings oJ the Annuαl Meeting oJ the Americαn Society oJ αίπίcαI Oncology, 1994, Abstract A137.
- Bonnier, Ρ, et al. «Clinical and biologic prognostic factors ίn breast cancer diagnosed during postmenopausal hormone replacement therapy» Ob- stetrics and Gynecology, 1995,85: 11.
- Bradlow, Η. Ι., et al. »Indole-3-carbinol: Α noνel approach to breast cancer preνention.» Appearing ίn «Cancer Preνention. From the Laboratory to the Clinic: Implications of Genetic, Molecular and Preνentiνe Research,» Annals oJ the New York Acαdemy oJ Sciences, September 1995, 768: 180-200. And also: «Multifunctional aspects of the action of indole-3-
- carbinol as an antitumor agent,» Annαls oJ the Νενν York Acαdemy oJ Sciences, 1999,889: 204-13.
- Brody, ]ane Ε. «Restoring ebbing hormones may slow aging.» Νενν York Times, ]uly 18, 1995, Ο.
- Coulan, C. Β., et al. «Chronic anovulation may increase postmenopau.sal. breast cancer ήsk.» ]oumal oJ the Ameιican Medical Association, 1983 , 249: 445-6.