Therapeutic program against the toxic load
The price we have to pay due to the industrial and technological revolution is heavy: a polluted planet, which may even become non-habitable in the near future.
During the past century, the changes that took place in our macrocosmos had not occurred in billions of years of revolution. The planet was burdened, along with all its living beings and inhabitants. The quality of the atmosphere, water and foods has changed dramatically.
The price we have to pay is heavy. Chronic and Autoimmune diseases are decimating the human population, and they are the leading causes of death, at least in the Western world.
Thousands of chemicals, radiations, drugs, poisons, and toxins burden human beings, and as a set they are termed toxic burden.
Unable to hide or adapt as a species to all these fast environmental changes, these particles and chemical compounds invade our body and they are stored in the adipose tissue of our cells; the smallest unit of life.
They are acting cumulatively, and they underlie until a critical concentration level in terms of quantity of combinations among them is reached, when the resulting biochemical deterioration of the cell is so great that our immune system cannot face it anymore, and Disease starts to manifest. The time of onset, its durability, as well as the rate of accumulation differs among individuals.
Autoimmune diseases, heart conditions, chronic syndromes, hypertension, diabetes, cancer, hormonal disorders, chronic infections, systemic diseases, fertility disorders and dozens of other diseases are caused either because our organism attacks its own altered biochemical cells (cannibalism – Autoimmunity), or because of the accumulated insufficiency of nutrients due to “poor-toxic” foods, which impede proper burning, and eliminate the production of vital elements and hormones from our organism.
Removing the toxic load from the cell
There are many methods or treatments that are used to “de-tox” our organism. Some focus on reducing “free radicals”, others on limiting them, but none in removing radiation, heavy metals and any other toxic load at the cellular level.
Equally popular is the administration of food supplements, vitamins, trace elements, and minerals, to limit “free radicals” and strengthen the immune system.
This administration may be detrimental, since a vitamin or a mineral never works on its own. In case of insufficiency of certain elements, the body may deprive bones and other tissues from the elements that are insufficient so that to maintain life, resulting in artificial insufficiency.
A glaring example is the administration of Vitamin B and Calcium, which leads immediately to Vitamin C insufficiency. The reason is that a vitamin, which acts as an organic catalyst, facilitates the necessary reactions, while for some other chemical reactions where vitamins are also essential but not present.
The excessive increase of a vitamin or other elements, either because they were prescribed or because someone just decided to take supplements affect negatively cellular biochemistry, and thus the organism.
Minerals circulating in the blood are like switches that stimulate glands. Artificial insufficiency may occur in this case.
The concept of balanced diet, as opposed to diets or famous diet programs, which is included in the toxic load reduction program, does not require participants to change their eating habits, and the additional administration of nutrients is balanced in terms of doses.
A key in the program is Vitamin B3, also known as Niacin, which has the capacity to massively mobilize the “toxic load” that is stored in our cells.
During the program we exchange “bad” for “good” fat.
Toxic substances have the ability to be stored within the cell’s adipose tissue; the program makes sure that this fat quantity is exchanged with new fat, in the form of oil.
The individual does not lose weight, s/he just exchanges toxic fat with new. The administered oils are natural organic compounds, including basic structural elements required by our body; in addition, lecithin is also administered, which helps in the decomposition of “bad” fat, so that to facilitate its elimination.
Both during and after the completion of the program, participants observe progressively a clear improvement of their health status, apart from their senses, feelings and wellbeing.
It is actually a unique but also very demanding program, offering substantial elimination of toxic load by approximately 95% for those who follow it.
Each cell of our body is regenerated, energy levels are restored, and our immune system is at its best. Toxic burdens that cause the disease or just underlie until its onset have been eliminated.
Patient Views and Opinions:
“I can remember myself before starting the Detox program, I was all the time stressed and nervy, from the time I woke up in the morning. I wasn’t sleeping well, I was waking up tired. I felt my stomach bloating really easily, I was getting angry and nervous with everything around me, especially with people without wanting this, but without being able to control it either. So, when I found out about the Detox program and its effectiveness, I decided to try it out.
I won’t go into too much detail, I will just tell you its effects on me.
After many years I can now sleep normally, I don’t wake up tired, my well-being and energy have been greatly improved. I don’t suffer from stomach bloating anymore, I am not feelings stressed or nervy, no itching at all. After the completion of the program I drink 80% less alcohol, I am feeling very energetic and very well. Finally everything turned out much better than I thought.”
“After the completion of the Detox program, I can say that, for me, it was a very important and energizing experience, both at physical and at mental level. A river flowed through each and every cell of my body and through all my emotional records; this was sometimes easy and relaxing, and others impetuous and painful, taking with it and expelling all the trash that was accumulating for years (radiation, anesthesia, trauma, negative thoughts). It healed hidden wounds, bringing up the internal power and the optimism that I need to move forward creatively and positively.
“I believe that the program I followed was beneficial for me both from a physical and from a mental point of view. Moreover, it helped me to overcome by 80% my dermatologic problem.
Now I think more calmly, I feel calmer, and I act more calmly, while I also think and act more effectively. I could go into more detail, but I generally believe this is a personal experience for each individual.
Within this deranged world, in all aspects, the DETOX program is a mental and physical experience.
It is a great gift for each one of us.”
“As a person, I do not easily trust others, and generally I could say that I am inherently suspicious in anything new and innovative. However, I am ready for new experiences if it’s something that moves me. I don’t know if I’ve always been like that, or whether this is the result of my lifestyle; I don’t remember myself being different, but probably I was. Thus, when I started the DETOX program, I was quite suspicious and doubtful about what I was told and whether it would really work so well.
Some days it was like hell, other days were normal. I was feeling as I was an actor of a film, the film of my life, all my good and bad characteristics. But in the end I forgot my bad experiences, and I could only see my positive characteristics. It would be unfair to say that this suggests I only got rid of the toxins. I also got rid of situations and experiences that are difficult to describe on a piece of paper.
You should try it to understand what I mean. I had a short trip back in time, seeing clearly all my mistakes and achievements; I don’t regret for what I did in the past, but I will definitely regret it if I do again in the future what I used to do. I am pleased and happy that I will make a new beginning.”
“I wake up with no pain in my joints, arms, feet, waist and back… I wake up feeling great… with mental clarity, no headaches, dizziness and migraine, which used to make me dysfunctional. I am more determined, more courageous, feeling “younger” and willing to do things, try new fields… much more alive, ultimately.
I wish it wasn’t coming to the end!! It was an experience!!
I want to thank all of you, and I am sorry I was tiring in the beginning, with all my doubts and distrust.”
From the first days, my reactions were incredible, and they helped me to believe that I really needed it… all those that were getting out of me could have been proven harmful for my health.
During the first days I was quite tired, and I was absorbed by the program, mainly due to the intensity of reactions. Later on, though, I realized that all tension and nervousness had gone. I have more energy and vitality, and greater mental clarity. I feel released, carefree and more relaxed… and now I can sleep for 8 hours, something impossible for me during the past years.
I also feel that I am better in my social life and with the people surrounding me.
Thank you all so much for your support!”
Altschul R, Hoffer A. The effect of nicotinic acid on hypercholesterolaemia. Can Med Assoc J 1960; 82: 783-5. Bandmann O, Vaughan J, Holmans P, et al. Association of slow acetylator genotype for Nacetyltransferase 2 with familial Parkinson’s disease. Lancet 1997;350:1136-1139. Berge KG, Canner PL. Coronary drug project: experience with niacin. Coronary Drug Project Research Group. Eur J Clin Pharmacol 1991; 40 Suppl 1: S49-51. Birjmohun RS, Hutten BA, Kastelein JJ, Stroes ES. Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials. J Am Coll Cardiol 2005; 45: 185-97. Biro S, Masuda A, Kihara T, and Tei C. Clinical implications of thermal therapy in lifestyle-related diseases. Exp Biol Med (Maywood). 2003 Nov; 228(10):1245-9. Bourre JM. Roles of unsaturated fatty acids (especially omega-3 fatty acids) in the brain at various ages and during ageing. J Nutr Health Aging 2004; 8: 163-74. Bulow J, Madsen J. Human adipose tissue blood flow during prolonged exercise II. Pflugers Arch 1978; 376: 41-5. Carroll DN, Roth MT. Evidence for the cardioprotective effects of omega-3 Fatty acids. Ann Pharmacother 2002; 36: 1950-6. Carlson LA, Oro L. The effect of nicotinic acid on the plasma free fatty acid; demonstration of a metabolic type of sympathicolysis. Acta Med Scand 1962; 172: 641-5. Carlson LA. Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review. J Intern Med 2005; 258: 94-114. Cecchini MA, Root DA, Rachunow JR, Gelb PM. Chemical Exposures at the World Trade Center: Use of the Hubbard Sauna Detoxification Regimen to Improve the Health Status of New York City Rescue Workers Exposed to Toxicants. Townsend Letter for Doctors and Patients 2006; 273: 58-65. CDC. National Center for Health Statistics. 2000.; NCI. SEER Cancer Statistics Review, 1973-1997. Center for Disease Control and Prevention, Department of Health and Human Services National Center for Environmental Health Third National Report on Human Exposure to Environmental Chemicals 2005 de Freitas AS, Norstrom RJ. Turnover and metabolism of polychlorinated biphenyls in relation to their chemical structure and the movement of lipids in the pigeon. Can J Physiol Pharmacol 1974; 52: 1080-94. Eisalo A, Luurila OJ. The Finnish sauna and cardiovascular diseases. Ann Clin Res 1988; 20: 267-70. Findlay GM, DeFreitas AS. DDT movement from adipocyte to muscle cell during lipid utilization. Nature 1971; 229: 63
5. Fontani G, Corradeschi F, Felici A, Alfatti F, Migliorini S, Lodi L. Cognitive and physiological effects of Omega-3 polyunsaturated fatty acid supplementation in healthy subjects. Eur J Clin Invest 2005; 35: 691-9. Friedberg SJ, Harlan WR Jr, Trout DL, Estes EH Jr. The effect of exercise on the concentration and turnover of plasma nonesterified fatty acids. J Clin Invest 1960; 39: 21520. Friedberg SJ, Sher PB, Bogdonoff MD, Estes EH Jr. The dynamics of plasma free fatty acid metabolism during exercise. J Lipid Res 1963; 4: 34-8. Green P, Hermesh H, Monselise A, Marom S, Presburger G, Weizman A. Red cell membrane omega-3 fatty acids are decreased in nondepressed patients with social anxiety disorder. Eur Neuropsychopharmacol 2006; 16: 107-13. Hathcock JN. Vitamins and minerals: efficacy and safety. Am J Clin Nutr 1997; 66: 427-37. Horstman D, Mendez J, Buskirk ER, Boileau R, Nicholas WC. Lipid metabolism during heavy and moderate exercise. Med Sci Sports 1971; 3: 18-23. Hubbard LR. Clear Body Clear Mind. Los Angeles: Bridge Publications, 2002 edition. Kawajiri K, Nakachi K, Imai K, et al. Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P4501A1 gene. FEBS Lett 1990;263:131-133. Khan JA, Forouhar F, Tao X, Tong L. Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert Opin Ther Targets 2007; 11: 695-705. Kihara T, Biro S, Ikeda Y, Fukudome T, Shinsato T, Masuda A, Miyata M, Hamasaki S, Otsuji Y, Minagoe S, Akiba S, and Tei C. Effects of repeated sauna treatment on ventricular arrhythmias in patients with chronic heart failure. Circ J. 2004 Dec; 68(12):1146-51. Kilburn KH, Warsaw RH, Shields MG. Neurobehavioral dysfunction in firemen exposed to polycholorinated biphenyls (PCBs): possible improvement after detoxification. Arch Environ Health 1989; 44: 345-50. Klaidman LK, Mukherjee SK, Adams JD Jr. Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide. Biochim Biophys Acta 2001; 1525: 136-48. Landrigan PJ, Lioy PJ, Thurston G et al. Health and environmental consequences of the world trade center disaster. Environ Health Perspect 2004; 112: 731-9. Leppaluoto J. Human thermoregulation in sauna. Ann Clin Res 1988; 20: 240-3. Leppaluoto J, Huttunen P, Hirvonen J, Vaananen A, Tuominen M, Vuori J. Endocrine effects of repeated sauna bathing. Acta Physiol Scand 1986; 128: 467-70. Levin B. Environmental Nutrition. Vashon Is, WA:HingePin Press;1999:179-84. Levin SM, Herbert R, Moline JM et al. Physical Health Status of World Trade Center Rescue and Recovery Workers and Volunteers — New York City, July 2002-August 2004. MMWR Morb Mortal Wkly Rep 2004; 53: 8 0 7 – 8 1 2 . Notes: Editor’s Note: The findings in this report indicate that a substantial proportion of program participants had new-onset and persistent upper and lower airway symptoms, musculoskeletal symptoms, and gastrointestinal symptoms. In addition, a substantial proportion of participants had respiratory abnormalities on spirometry. This preliminary analysis is consistent with earlier reports from WTC screening programs conducted by FDNY (4,5), which documented a substantial proportion of respiratory symptoms in emergency response workers. These findings suggest a need for continued monitoring and appropriate treatment of WTC responders. Lichtenstein P, Holm NV, Verkasalo PK, et al. Environmental and heritable factors in the causation of cancer. N Liska DJ ad Bland JS Emerging clinical Science of bifunctional support for detoxification. Townsend Letter Oct 2002 Liska DJ. The detoxification enzyme systems. Altern Med Rev. 1998;3(3):187-98. Eng J Med. 2000;343:78-85. Logan AC. Neurobehavioral aspects of omega-3 fatty acids: possible mechanisms and therapeutic value in major depression. Altern Med Rev 2003; 8: 410-25. Magni G, Amici A, Emanuelli M, Orsomando G, Raffaelli N, Ruggieri S. Enzymology of NAD+ homeostasis in man. Cell Mol Life Sci 2004; 61: 19-34. McKenney JM, Proctor JD, Harris S, Chinchili VM. A comparison of the efficacy and toxic effects of sustained- vs immediate-release niacin in hypercholesterolemic patients. JAMA 1994; 271: 672-7. Meyers CD, Kashyap ML. Management of the metabolic syndrome-nicotinic acid. Endocrinol Metab Clin North Am 2004; 33: 557-75, vii. Mitjavila S, Carrera G, Fernandez Y. Evaluation of the toxic risk of accumulated DDT in the rat: during fat mobilization. Arch Environ Contam Toxicol 1981; 10: 471-81. Moore RB, Anderson JT, Taylor HL, Keys A and Frantz ID (1968) Effect of dietary fat on the fecal excretion of cholesterol and its degradation products in man. J Clinical Investigation 47:1517-1534. Moser GA, McLachlan MS. A non-absorbable dietary fat substitute enhances elimination of persistent lipophilic contaminants in humans. Chemosphere 1999; 39: 1513-21. Muir T, Zegarac M. Societal costs of exposure to toxic substances: economic and health costs of four case studies that are candidates for environmental causation. Environ Health Perspect. 2001;109Suppl 6:885-903. Nebert DW, Petersen DD, Puga A. Human AH locus polymorphism and cancer: inducibility of CYP1A1 and other genes by combustion products and dioxin. Pharmacogenetics 1991;1:68-78. Okamoto H, Ishikawa A, Yoshitake Y et al. Diurnal variations in human urinary excretion of nicotinamide catabolites: effects of stress on the metabolism of nicotinamide. Am J Clin Nutr 2003; 77: 406-10. O’Keefe JH Jr, Abuissa H, Sastre A, Steinhaus DM, Harris WS. Effects of omega-3 fatty acids on resting heart rate, heart rate recovery after exercise, and heart rate variability in men with healed myocardial infarctions and depressed ejection fractions. Am J Cardiol 2006; 97: 1127-30. Olmstead MJ. Heavy metal sources, effects, and detoxification. Altern Ther Complement Med.
2000;Dec;347-354. Pall ML, Satterle JD. Elevated nitric oxide/peroxynitrite mechanism for the common etiology of multiple chemical sensitivity, chronic fatigue syndrome, and posttraumatic stress disorder. Ann N Y Acad Sci. 2001;933:323-29. Parsons WB Jr, Flinn JH. Reduction of serum cholesterol levels and beta-lipoprotein cholesterol levels by nicotinic acid. AMA Arch Intern Med 1959; 103: 783-90. Perasalo J. Traditional use of the sauna for hygiene and health in Finland. Ann Clin Res 1988; 20: 220-3. Pike NB. Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid. J Clin Invest 2005; 115: 3400-3. Protein Data bank October 2006: Cytochrome p450 Racciatti D, Vecchiet J, Ceccomancini A, Ricci F, Pizzigallo E. Chronic fatigue syndrome following a toxic exposure. Sci Total Environ. 2001;270(1-3):27-31. Roberts MS, Magnusson BM, Burczynski FJ, Weiss M. Enterohepatic circulation: physiological, pharmacokinetic and clinical implications Clin Pharmacokinet. 2002;41 (10):751-90. Rozman K. Intestinal excretion of toxic substances. Arch Toxicol Suppl 1985; 8: 87-93. Rozman K, Ballhorn L, Rozman T. Mineral oil in the diet enhances fecal excretion of DDT in the rhesus monkey. Drug Chem Toxicol 1983a; 6: 311-6. Rozman K, Rozman T, Greim H. Stimulation of nonbiliary, intestinal excretion of hexachlorobenzene in rhesus monkeys by mineral oil. Toxicol Appl Pharmacol 1983b; 70: 255-61. Rubic T, Trottmann M, Lorenz RL. Stimulation of CD36 and the key effector of reverse cholesterol transport ATPbinding cassette A1 in monocytoid cells by niacin. Biochem Pharmacol 2004; 67: 411-9. Rudel RA, Brody JG, Spengler JD, et al. Identification of selected hormonally active agents and animal mammary carcinogens in commercial and residential air and dust samples. J Air Waste Mange Assoc. 2001;51(4):499-513. Sazhenin, G. I. and Parshkov, E. M. Assessment of Antioxidative and Phagocytic Status of Organism during Detoxification of Persons Contaminated with Radionuclides in Territories of Briansk blast. International Conference On Human Detoxification. 97. International Academy of Detoxification Specialists. Schnare DW, Denk G, Shields M, Brunton S. Evaluation of a detoxification regimen for fat stored xenobiotics. Med Hypotheses 1982; 9: 265-82. Schnare, D. W., Ben, M., and Shields, M. G. Body Burden Reduction of PCBs, PBBs and Chlorinated Pesticides in Human Subjects. Ambio 13(5-6), 378-380. 84. SHEEHAN D, G MEADE, V FOLEY, C DOWD Biochem. J.  360 Structure, function and evolution of
glutathione transferases : implications for classification of non-mammalian members of an ancient enzyme superfamily Sherer TB, Betarbet R, Greenamyre JT. Environment, mitochondria, and Parkinson’s disease. Neuroscientist. 2002;8(3):192-7. Shepherd J, Stewart JM, Clark JG and Carr K (1980) Sequential changes in plasma lipoproteins and body fat composition during polyunsaturated fat feeding in man. Br J Nutr 44:265-271. Shimada T. Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons. Drug Metab Pharmacokinet 2006; 21: 257-76. Sies H, Brigelius R, Wefers H, Muller A, Cadenas E. Cellular redox changes and response to drugs and toxic agents. Fundam Appl Toxicol 1983; 3: 200-8. Silkworth JB, Brown JF Jr. Evaluating the impact of exposure to environmental contaminants on human health. Clin Chem. 1996;42:8(B):1345-49. Taylor AW, Shoemann DS, Lovlin R, Lee S. Plasma free fatty acid mobilization with graded exercise. J Sports Med Phys Fitness 1971; 11: 234-40. Thorton JW, McCally M, Houlihan J 2002 Public Health Reports vol. 117 Biomonitoring of industrial pollutants: Health and Policy implications of the Chemical Body Burden. Tretjak, Z., Beckmann, S., Tretjak, A., and Gunnerson, C. Occupational, Environmental, and Public Health in Semic: A Case Study of Polychlorinated Biphenyl (PCB) Pollution. Post-Audits of Environmental Programs and Projects; Proceedings, Environmental Impact Analysis Research Council / ASCE , 57-72. 89. Tretjak Z, Shields M, Beckmann SL. PCB reduction and clinical improvement by detoxification: an unexploited approach? Hum Exp Toxicol 1990; 9: 235-44. Tsyb, A. F., Parshkov, E. M., Barnes, J., Yarzutkin, V. V., Vorontsov, N. V., and Dedov, V. I. Rehabilitation of a Chernobyl Affected Population Using a Detoxification Method. Proceedings of the 1998 International Radiological Postemergency Response Issues Conference. 98. U.S. Environmental Protection Agency. Yamazaki M, Suzuki H,Sugiyama Y. Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics Pharm Res. 1996 Apr;13(4):497-513 World Health Organization 2003 Global Strategy on diet, physical activity and health Wang W, Basinger A, Neese RA et al. Effect of nicotinic acid administration on hepatic very low density lipoproteintriglyceride production. Am J Physiol Endocrinol Metab