Every human body is made up of approximately 13 trillion cells. From the moment of conception, every cell and therefore the tissues and organs begin an aging process.

At some point in life and then, often after the age of 30, the first signs of aging begin to occur. For example, metabolism begins to decline gradually starting around the age of 20.

There are many factors that affect aging: genetics, diet, hormonal changes, exercise, illness and a host of other factors.

A number of notable research studies since the 1990s have identified genes, that can profoundly influence the rate at which cells and animals age.

 

Prevention

The cells become less able to divide, the telomeres, namely the ends of the chromosomes inside each cell, gradually become shorter until they eventually become so short that the cell dies, toxins accumulate, the connective tissue between the cells becomes harder, the maximum functional capacity of many organs decreases.

We can not change our genes and we can not stop the passage of time. However, through lifestyle changes and especially through cellular care and hormonal balance we can reduce the risk and speed of aging.

 

Dealing with aging

The aging process does not discriminate. It starts early and affects every important organ of the body.

Both the adoption of a proper lifestyle (diet, physical and mental exercise, good psychology, smoking cessation) and biological and cellular care at the level of hormones and nutrient deficiencies can become a catapult to the battle with time.

 

Cellular health and longevity

Health is essentially determined by the building blocks of our body, the cells. Good cellular health means that all the important molecules that make up the cell, the proteins, mitochondria and DNA function properly and are free of damage.

Aging causes deterioration of cellular health. In fact, aging is not just a process. It is more like a series of different changes happening at the same time. A 2013 review published in Cell Magazine identified nine different features of aging, such as “mitochondrial dysfunction” – which occurs when the cellular metabolic motor stops working properly – and “cell aging” – when cells stop dividing as part of the biological process.

 

Epigenetic and Cellular Rehabilitation

Cellular deficiencies can be identified by conducting cellular level diagnostic tests.

Isolation of factors that can biochemically alter cells should only be found through specialized cell tests. Restoration is then done by administering the appropriate micronutrients, so that the cells can heal themselves.

Tests, either molecular or metabolic, create a complete diagnostic cell profile, as they can evaluate with absolute accuracy what exactly is happening at the cellular level.

 

 

References:


  1. McDonald, Roger B. (7 June 2019), “Basic Concepts in the Biology of Aging”, Biology of Aging, Garland Science, pp. 1–36, doi:10.1201/9780429030642-1, ISBN 978-0-429-03064-2
  2. Nutman AP, Bennett VC, Friend CR, Van Kranendonk MJ, Chivas AR (September 2016). “Rapid emergence of life shown by discovery of 3,700-million-year-old microbial structures”. Nature (Submitted manuscript). 537 (7621): 535–538. Bibcode:2016Natur.537..535N. doi:10.1038/nature19355. PMID 27580034. S2CID 205250494.
  3. Pathai S, Shiels PG, Lawn SD, Cook C, Gilbert C (March 2013). “The eye as a model of ageing in translational research–molecular, epigenetic and clinical aspects”. Ageing Research Reviews. 12 (2): 490–508. doi:10.1016/j.arr.2012.11.002. PMID 23274270. S2CID 26015190.
  4. Mehta S (September 2015). “Age-Related Macular Degeneration”. Primary Care. 42 (3): 377–91. doi:10.1016/j.pop.2015.05.009. PMID 26319344.
  5. Brunet Lab: Molecular Mechanisms of Longevity and Age Related Diseases. Stanford.edu. Retrieved on 11 April 2012.
  6. Janssens GE, Meinema AC, González J, Wolters JC, Schmidt A, Guryev V, et al. (December 2015). “Protein biogenesis machinery is a driver of replicative aging in yeast”. eLife. 4: e08527. doi:10.7554/eLife.08527. PMC 4718733. PMID 26422514.
  7. “Mitochondrial Theory of Aging and Other Aging Theories”. 1Vigor. Retrieved 4 October 2013.
  8. Marioni RE, Shah S, McRae AF, Chen BH, Colicino E, Harris SE, et al. (January 2015). “DNA methylation age of blood predicts all-cause mortality in later life”. Genome Biology. 16 (1): 25. doi:10.1186/s13059-015-0584-6. PMC 4350614. PMID 25633388.
  9. Saey TJ (15 December 2016). “Proteins that reprogram cells can turn back mice’s aging clock”. Retrieved 19 December 2016.
  10. Callaway E (2016). “Destroying worn-out cells makes mice live longer”. Nature. doi:10.1038/nature.2016.19287. S2CID 181078450. Retrieved 25 May 2019.
  11. Hall BM, Balan V, Gleiberman AS, Strom E, Krasnov P, Virtuoso LP, et al. (July 2016). “Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells”. Aging. 8 (7): 1294–315. doi:10.18632/aging.100991. PMC 4993332. PMID 27391570.
  12. Junnila RK, List EO, Berryman DE, Murrey JW, Kopchick JJ (June 2013). “The GH/IGF-1 axis in ageing and longevity”. Nature Reviews. Endocrinology. 9 (6): 366–376. doi:10.1038/nrendo.2013.67. PMC 4074016. PMID 23591370.
  13. Lee JH, Kim EW, Croteau DL, Bohr VA (September 2020). “Heterochromatin: an epigenetic point of view in aging”. Experimental & Molecular Medicine. 52 (9): 1466–1474. doi:10.1038/s12276-020-00497-4. PMID 32887933.
  14. “Science for Life Extension”. Science against aging foundation. Archived from the original on 18 February 2015. Retrieved 3 February 2015.

 

Read more


Telomeres and Aging

Cellular Hydration and Anti-Aging

What is your biological age?